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In 1931, the diathermy machine was introduced to treat paresis, a form of paralysis. Before, physicians had induced a high fever in paretic patients by injecting them with malaria germs. While the malarial fever did help some patients, the danger of dying of malaria outweighed the benefits. When penicillin was discovered, it replaced the diathermy machine, chiefly because it was dramatically effective for treating syphillis, the major cause of paresis. In 1932, the hospital established its first community-based treatment center when it set up a clinic for mental health education and consultation in the New Madrid County Courthouse. Other clinics were set up in Mississippi and Scott Counties and today clinics can be found in Sikeston, Cape Girardeau, Kennett and West Plains. On June 6, 1940, Dr. Paul Schrader performed the first lobotomy. In the first months of 1940, 64 major lobotomies were performed at the hospital. All told, 200 lobotomies were performed at the hospital, the last in 1943. Electroshock therapy was introduced in 1942. During the 1930s and '40s, several WPA projects were completed on the hospital grounds, including utility tunnels, storm sewers and a new dairy barn. The 1950s and '60s were a period of overcrowding for the hospital. In 1954, the average daily patient population was 1,879. The recommended capacity was 1,600. By 1970, the hospital was serving 25 counties and the Alcoholism Treatment Center had been expanded to handle drug abuse patients. Treatments in practice included recreation, music and occupational therapy.
 
In 1931, the diathermy machine was introduced to treat paresis, a form of paralysis. Before, physicians had induced a high fever in paretic patients by injecting them with malaria germs. While the malarial fever did help some patients, the danger of dying of malaria outweighed the benefits. When penicillin was discovered, it replaced the diathermy machine, chiefly because it was dramatically effective for treating syphillis, the major cause of paresis. In 1932, the hospital established its first community-based treatment center when it set up a clinic for mental health education and consultation in the New Madrid County Courthouse. Other clinics were set up in Mississippi and Scott Counties and today clinics can be found in Sikeston, Cape Girardeau, Kennett and West Plains. On June 6, 1940, Dr. Paul Schrader performed the first lobotomy. In the first months of 1940, 64 major lobotomies were performed at the hospital. All told, 200 lobotomies were performed at the hospital, the last in 1943. Electroshock therapy was introduced in 1942. During the 1930s and '40s, several WPA projects were completed on the hospital grounds, including utility tunnels, storm sewers and a new dairy barn. The 1950s and '60s were a period of overcrowding for the hospital. In 1954, the average daily patient population was 1,879. The recommended capacity was 1,600. By 1970, the hospital was serving 25 counties and the Alcoholism Treatment Center had been expanded to handle drug abuse patients. Treatments in practice included recreation, music and occupational therapy.
  
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In 1972, the Blair Building, the last of the new buildings, was opened as a psychiatric medical facility. By 1975, the average daily population had fallen to 521 patients at the state hospital, but an average of 600 people were treated monthly on an outpatient basis. In 1978, Dr. Hoctor retired after a 53-year career with Farmington State Hospital, and the institution marked its 75th anniversary. By 1982, the population had fallen to 320 on the hospital grounds, the level stipulated under the conversion plan. The majority of the original grounds, and buildings for State Hospital Number 4 became part of the Missouri Department of Corrections.<ref>Published by THE DAILY JOURNAL, Flat River, St. Francois Co. MO, Fri. April 24, 1987 in a supplement ''"Reflections: View of the Past - A Look To the Future"'' written by Peggy O'Farrell, Daily Journal News Editor</ref> In 1987 the facility was renamed Southeast Missouri Mental Health Center and the non-forensic patients were moved into the new building which is now known as the Danny Staples building, where Adult Psychiatric Services are provided. The Hoctor building, named after Dr. Hoctor, is now used along with the Blair building to house the SORTS program-Sexual Offender Rehabilitation Services.
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In 1972, the Blair Building, the last of the new buildings, was opened as a psychiatric medical facility. By 1975, the average daily population had fallen to 521 patients at the state hospital, but an average of 600 people were treated monthly on an outpatient basis. In 1978, Dr. Hoctor retired after a 53-year career with Farmington State Hospital, and the institution marked its 75th anniversary. By 1982, the population had fallen to 320 on the hospital grounds, the level stipulated under the conversion plan and became part of the Missouri Department of Corrections.<ref>Published by THE DAILY JOURNAL, Flat River, St. Francois Co. MO, Fri. April 24, 1987 in a supplement ''"Reflections: View of the Past - A Look To the Future"'' written by Peggy O'Farrell, Daily Journal News Editor</ref>
  
 
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